Feige had stated on potential future Daredevil films, as "there are many more stories to be told with old Hornhead and we'd love to tell them someday". Avi Arad has also said that a sequel will begin development once the rights go from 20th Century Fox to Marvel Studios. Director Mark Steven Johnson showed interest in returning to direct with the Born Again storyline, as well as suggesting Mr. Fear as a possible villain. During 2004, Ben Affleck shot a cameo role for the spin-off film, Elektra, at the request of Daredevil co-star Jennifer Garner. That October, Affleck stated he would only return in the lead role if Fox would renegotiate to tell the darker stories of Daredevil, and showed interest in a Kevin Smith graphic novel which included Mysterio, as well as the Born Again storyline. However, in November 2006, Affleck said that he would never reprise the role, having felt "by playing a superhero in Daredevil, I have inoculated myself from ever playing another superhero... Wearing a costume was a source of humiliation for me and something I wouldn't want to do again soon". Despite this, Affleck would later sign on to portray the DC superhero, Bruce Wayne / Batman, in Batman v Superman: Dawn of Justice.
In July 2006, Michael Clarke Duncan showed interest in returning for the role of the Kingpin, but said that he would not be willing to gain weight as he felt "comfortable" being down to 270 pounds. However, he jokingly showed willingness to change his mind if he was offered $20 million. Duncan suggested that the character is portrayed to have been training a lot in jail in order to become faster in combat against Daredevil, also working as a way to fit his weight loss into the story. Duncan would later go on to reprise his role as the Kingpin in an episode of the animated series: Spider-Man: The New Animated Series.